Northern Ireland manager Ian Baraclough revealed the defender/midfielder will not be travelling with the rest of the squad for the challenge match at Stade de Luxembourg.
McNair limped out of Middlesbrough’s FA Cup quarter-final defeat to Chelsea at the Riverside Stadium on Saturday.
Baraclough said McNair will stay behind in Northern Ireland for treatment on a bruised foot.
He did not say if the defender/midfielder will be available for the home friendly against Hungary next Tuesday (29 March).
The Northern Ireland boss further revealed that Liverpool defender Conor Bradley has not yet joined up with the squad. Bradley has a knee injury which is being monitored by his club.
And he also said first choice goalkeeper Bailey Peacock-Farrell (Sheffield Wednesday, on loan from Burnley) will not be travelling to Luxembourg but will join up with the squad for the game against Hungary.
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