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Research Fellow – Bioinformatics / Molecular Epidemiology – Child Health and Development – Singapore Institute for Clinical Sciences
A two-year position at the Singapore Institute for Clinical Sciences is available to a highly-motivated postdoctoral researcher in bioinformatics and/or molecular epidemiology in the area of reproductive, perinatal, and paediatric epidemiology, with particular training and expertise in transcriptomics and epigenomics. The candidate will develop a competitive research portfolio using class-leading multimodal data from up to three longitudinal birth cohort studies (GUSTO, N = ~1200 enrolled; S-PRESTO, N = ~1000 enrolled; and MAMS, N = ~2000 anticipated) in collaboration with local research hospitals, top research universities, government research entities, and a broad network of international collaborators.
The cohorts represent world-class efforts in deep pheno- and geno-typing, with available measures including: clinical characteristics; sociodemographics and spatiotemporal data; parenting and child behaviors; child neurodevelopmental assessment; state-of-the-art brain and body imaging; and numerous –omics (metabolome; (epi)genome; transcriptome; microbiome). A large biorepository (e.g. hair, saliva, urine, blood) has been formed. Details on available data and samples for GUSTO/S-PRESTO can be found at: gustodatavault.sg
The Fellow will work closely with the PI to develop research based on two competitively funded projects:
1. Placental multi-omics linking in vitro fertilization (IVF) and longitudinal child cardiometabolic outcomes. The Fellow will develop and apply methods to investigate mediating mechanisms between IVF and child outcomes utilizing placental multi-omic data (genomic, DNA methylation, and RNAseq).
2. The relationships between paternal pre- and perinatal factors on pregnancy and offspring health.
The Fellow will not have teaching responsibilities and will be expected only to conduct research and knowledge dissemination activities (i.e. data analyses, manuscript writing, grant writing, conference presentations, lectures, workshops, scientific community engagement, etc.).
Opportunities for further training, mentorship, and collaboration, including out-placement with a data science industry partner may be possible. Incumbent will have access to a highly interdisciplinary local research environment at SICS; A*STAR; Duke-NUS; NUS School of Public Health; NUS School of Medicine; NTU, etc. with the goal of supporting the incumbent’s long-term career goals. SICS is a dynamic working environment with dozens of postdoctoral peers working in such diverse domains as eating behaviors, neurodevelopment, allergy, growth and metabolism, parenting, -omics, brain and body imaging, and oral health.
For more information about the position, please contact the PI Jon Huang (jonathan_huang@sics.a-star.edu.sg). More information about the lab can be found at: jonhuang.org. The research group and PI are highly collaborative and encourage a strong work-life balance. Salary and benefits are highly global competitive and Singapore is a top global city with easy access to numerous destinations around Southeast Asia and the wider region.
Applications to the position should be emailed to the PI and biostats@sics.a-star.edu.sg and include: A brief cover letter describing research experience and goals, CV, and 2 representative publications (or completed manuscripts). Applicants who are near completion of their doctorate are eligible.
The position will be open until filled. Apologies as only short-listed candidates will be notified.
Qualification & Field of Study: PhD in quantitative biomedical discipline e.g. Epidemiology, Biostatistics, Statistics, Bioinformatics, with experience in human cohort studies and multi-omics.
Min. Years of Experience:
3 years of relevant research, including concurrent with doctorate
Other Requirements (e.g. Skills, Competencies)
Required:
Preferred:
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